1. In Vivo

Exact Laboratories Inc.

Colorectal cancer screening.

As an electrical engineer, Stanley Lapidus has always taken a practical approach to medicine. An inventor who says his goal is “to make medicine work,” he founded Cytyc Corp. in 1987 to develop more accurate cervical cancer screening tests. Lapidus initially started the company to apply his knowledge of computerized image analysis to cytology. But it was his unique automated slide preparation system, developed to aid the diagnostic technology, that became an unexpected success. The new sample preparation technique alone improved the detection of the disease by 18%. Cytyc is now a public company with a market cap of $270 million.

Lapidus saw the colorectal cancer screening market as a similar challenge. “I want to work in areas where improved diagnostics...

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