The process of hunting for drugs is now markedly different than it was a few decades ago, partly because research organizations are much bigger and market pressures more intense. Technology has catalyzed the biggest shifts, decreasing the role of individuals and putting more emphasis on method than conceptualization. But the high-tech methods haven't been as productive as expected, and so research executives are increasingly considering which of the traditional ways might be worth recapturing.
By Deborah Erickson
It's easy to see why executives pondering research productivity sometimes daydream about cloning famous drug hunters. Many important products—even entire classes of drugs—owe their existence to just a few individuals....
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