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Son-Of-Xigris Goes to Biotech--Where it Belongs?

When Eli Lilly licensed the follow-on drug candidate to sepsis treatment Xigris to Cardiome, it was a tacit acknowledgment that this family of specialist products may be better suited to biotech. Perhaps they should have done the same with Xigris.

At first glance, Eli Lilly & Co. ’s licensing deal with Cardiome Pharma Corp. on April 30 may not have appeared particularly remarkable. Lilly has after all been one of the more active Big Pharma out-licensers, and LY458202, in Phase I trials for cardiogenic shock, looked rather too niche for the larger firm—but perfectly suited to a cardiovascular-focused biotech. [See Deal]

But this wasn’t any old out-licensing deal. LY458202, also known as GED-aPC, is an engineered analog of recombinant human activated...

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