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With DxS, Qiagen Moves into Personalized Medicine

Qiagen has bought up DxS, a private UK-based provider of molecular tests including one for the mutant oncogene KRAS. Like the June 2009 deal by Labcorp. for Monogram Biosciences, it shows how IVD companies with very different business models are moving towards a common ground in personalized medicine and disease management.

Qiagen NV's $1.42 billion acquisition of Digene Corp. in mid-2007 surprised the industry. [See Deal] With a business model geared towards high-volume, platform-oriented economies of scale rather than high-value, focused content like Digene's molecular diagnostic HPV test, the Dutch sample prep and assay specialist was not seen as a major player in the evolving molecular space. Now, Qiagen has bought up Qiagen Manchester Ltd., a privately held UK-based provider of molecular tests including one for the mutant oncogene KRAS, the companion diagnostic featured as of July 2009 on the labels of the EGF receptor targeting drugs panitumumab (Vectibix) and cetuximab (Erbitux) (cetuximab) for metastatic colon cancer, from Amgen Inc. and Bristol-Myers Squibb Co. and partner ImClone Systems Inc. (part of Eli Lilly & Co.), respectively. [See Deal][See Deal][See Deal]

Qiagen is paying $95 million in cash for DxS, with the promise of an additional $35 million conditioned on achievement...

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