The Power Of Pradaxa: Physicians Weigh In

With the worldwide market for novel oral anti-coagulants Pradaxa, Xarelto, and apixiban pegged at as much as $10 billion, how these drugs fare with physicians - and, importantly, payors - provides a case study for future big drug launches in an era where health care costs are a key consideration.

Big Pharmas Johnson & Johnson, Bayer AG, Bristol-Myers Squibb Co. and Pfizer Inc. have a lot riding on the ultimate commercial success of their oral anti-coagulants, Xarelto (rivaroxaban) and apixiban. So does Boehringer Ingelheim GMBH, which claimed first-to-market bragging rights in the US with the October 2010 FDA approval of its own direct thrombin inhibitor, Pradaxa (dabigatran). With analysts estimating the worldwide market for these medicines potentially reaching $10 billion, these three oral anti-coagulants could represent the next frontier for blockbuster therapies. How these drugs fare with physicians – and, importantly, payors – will provide a case study for future big drug launches in an era where not just clinical outcomes, but also health care costs, are a key consideration. ( See "Oral Anticoagulants Market Snapshot: Big Bucks, But Payers Are On Guard," "The Pink Sheet," October 25, 2010 Also see "Oral Anticoagulants Market Snapshot: Big Bucks, But Payers Are On Guard" - Pink Sheet, 25 October, 2010..)

Physicians are evaluating not just how the three medicines stack up against each other, but also versus the decades-old generic...

More from Archive

Final Chance To Have Your Say: Take Our Reader Survey This Week

 

Editor’s note: This is your final call to participate in the survey to better understand our subscribers’ content and delivery needs. The deadline is 20 September.

Early Development Deals: Ipsen's Strategy For Biomarker-Driven Success

 

Mary Jane Hinrichs, Ipsen’s head of early development, talks to In Vivo about getting ahead of the competition by securing deals for candidates before they enter Phase I trials.   

Shape Our Content: Take The Reader Survey

 

Editor’s note: We are conducting a survey to better understand our subscribers’ content and delivery needs. If there are any changes you’d like to see in the coverage topics, content format or the method in which you receive and access In Vivo, or if you love it how it is, now is the time to have your voice heard.

In Partnership with Cerba Research

Prioritizing Safety in CAR-T Therapy: Patient Monitoring with Cerba Research’s Testing Portfolio

The cell and gene therapy (CGT) clinical trial landscape in general and CAR-T cell clinical trials in particular are a special focus for the FDA, EMA, and other regulatory agencies. The whole industry is thus aware of the recent FDA safety investigation and requirements for labeling CAR therapy products.

More from In Vivo

Rising Leaders 2025: Doxie Jordan, From UNC Graduate To Global Market Strategist

 
• By 

Bristol Myers Squibb executive Doxie Jordan discusses his path to global commercial leadership and the principles guiding pharmaceutical market strategy

Podcast: Brain+ CEO Discusses “Groundbreaking” Potential Of CST Assistant For Dementia Patients

 

Devika Wood, CEO of Brain+, explains the importance of developing health tech solutions for dementia and the growing need to both raise awareness and improve overall access to nondrug interventions like CST.

Behind The Buyout: Dispatches From The Dealmaking Table

 
• By 

In a challenging funding environment for biopharma, strategic dealmaking has become a critical growth engine. In Vivo explores what it truly takes to navigate high-stakes acquisitions and partnerships, drawing on insights from seasoned industry leaders.