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Start-Up Previews (05/2010)

Executive Summary

A preview of the emerging health care companies profiled in the current issue of Start-Up. "As Drug-Resistant Microbes Rise, Antibiotic Start-Ups Need Savvy Investors," features profiles of Cempra Pharmaceuticals, DesignMedix, Kenta Biotech and MGB Biopharmaceuticals. Plus these Start-Ups Across Health Care: CardioPhotonics, Eureka Genomics, Invuity and OrthoSensor.

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Invuity Inc.

In the never-ending push for less invasive surgeries, lighting systems for better visualization have been largely overlooked. Crude fiberoptic tools have proved less than ideal when performing open surgery through small apertures that rely on direct visualization via the surgeon’s own sight. But now physicians have a new option for enhanced visualization: optical waveguide devices that transmit high-intensity, off-axis illumination into the desired surgical field using principles of internal reflection. This is one of the key aspects of technology from Invuity Inc., which offers three families of customized optical waveguide tools.

CardioPhotonics LLC

CardioPhotonics' HeartLight monitors fluid volumes in real time and is normalized to patients during surgery. The company believes that the ability to accurately assess the patient’s condition and consequently avoid the over- or underadministration of fluids will reduce post-surgical complications that can prolong hospital stay and increase health care costs.

OrthoSensor Inc.

OrthoSensor Inc. has combined electronics, communications and orthopedics technology to enable an array of intelligent orthopedic devices to assist in placement and postoperative monitoring of implants and patients’ musculoskeletal health. This enhanced accuracy and versatility should help health care providers deliver evidence-based medicine that can lead to improved quality and coordination of care. OrthoSensor thinks its technology platform will be applicable to virtually all areas of musculoskeletal disease.

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