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Start-Up Previews (02/2011)

A preview of the emerging health companies profiled in the current issue of Start-Up. This month's profile group, "Emerging MS Treatments: Reading the Gilenya Tea Leaves," includes profiles of Allozyne, GeNeuro, Nuron Biotech and Receptos. Plus these Start-Ups Across Health Care: Intralink-Spine, NinePoint Medical, PanOptica and Urovalve.

Allozyne Inc.'s novel interferon beta drug candidate is now in Phase I clinical trials for MS. The company used its proprietary linker technology to attach PEG to interferon, and believes that will allow more drug to be loaded into a dose and lead to a product that could be injected as infrequently as once per month. Moreover, it thinks its PEG conjugate should reduce tolerance problems and improve half-life over current interferons.

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