Indicated for many types of acute and chronic wounds, negative pressure wound therapy kicks off many mechanisms useful in wound healing. However, the devices aren't used in all patients for whom they're indicated for reasons that have to do with inconvenience, logistics and quality of life. Spiracur offers the same negative pressure therapy in a small, entirely mechanical, tether-free disposable device that replaces the cumbersome electric pumps that dominate the market today.

Patent foramen ovale can be a contributing factor for stroke, chronic migraine, decompression sickness and obstructive sleep apnea. SeptRx Inc.'s percutaneous device for treating PFO is unique in that it mirrors the anatomy of the flat tunnel of tissue that characterizes PFO. Not only is the device itself flat, but its frame laterally stretches the tunnel to keep it flat and bring the tissue surfaces in contact.

Life Recovery Systems HD LLC's ThermoSuit system lowers body temperatures to the therapeutic hypothermia range in a mere 20 to 30 minutes by bringing nearly the entire surface of the patient's skin into direct contact with continuous flowing ice water.