Branded Life After Lipitor: Pharma Targets Unmet Needs In Dyslipidemia

Statins represent a high standard of care for managing high blood cholesterol, bolstered by a strong evidence base, but new targets like PCSK9 and CETP are nevertheless stealing the spotlight nowadays. Whether new drugs, if they make it to market, will be used beyond narrow, targeted population segments is uncertain and will depend on results from large-scale outcomes studies showing significant efficacy and, importantly, reassurance of a solid safety profile.

Emblematic of an era, Pfizer Inc.’s enormously successful statin Lipitor (atorvastatin) now has a seat on the train to the ghost town of bygone blockbusters.

Though it was late of its kind to gain FDA-approval, Lipitor became a best seller, reaching sales of $5.3 billion...

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