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Actelion Braces For Tracleer Patent Cliff With New Drugs, New Data Standards

Actelion is preparing for the patent loss on its leading PAH drug not simply with a new product, but by setting a new efficacy standard across the entire PAH community.

Switzerland’s Actelion Pharmaceuticals Ltd. may be only 16 years old, but it faces a very grown-up problem: the patent expiry of its blockbuster pulmonary arterial hypertension (PAH) drug, Tracleer (bosentan), which accounts for almost 90% of sales.

The challenge isn’t unusual – most Big Pharma and many mid-caps have lost or soon face losing billions to generics....

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