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Noninvasive Prenatal Screening: Battleground In Diagnostics Innovation

Four companies have brought noninvasive prenatal testing to the market within the past two years. Its dramatic, rapid uptake has triggered a backlash among many geneticists, who fear the consequences of a poorly understood – and overhyped – technology.

Since the commercial introduction of Sequenom Inc.’s MaterniT21 test in October 2011, noninvasive prenatal testing (NIPT) has become the hottest – and most controversial – area of clinical genomics.

The drive toward NIPT was rooted in the bold dream of replacing invasive diagnostic testing for genetic disorders, which entails...

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