One Test’s Odyssey: Cancer Of Unknown Origin

In recent years Pathwork Diagnostics Inc. and Rosetta Genomics Ltd. have developed tests that use the molecular makeup of the cancer cells to provide insight on the cancer’s origin.

In recent years two companies have attempted to commercialize molecular diagnostic assays designed to provide clinicians improved information about cancers of unknown primary (CUP). The prognosis for CUP patients is particularly poor. Treatment options are limited as, by definition, patients present with metastatic disease, and because very little is known about the origin of the cancer. Both Pathwork Diagnostics Inc. and Rosetta Genomics Ltd. developed tests that use the molecular makeup of the cancer cells to provide insight on the cancer’s origin.

Pathwork Diagnostics’ test was cleared by the FDA in 2008 (for frozen samples) and again in 2010 (for formalin-fixed, paraffin-embedded...

More from Archive

More from In Vivo

Strategic Surprises: The Drugs That Rewrote The Forecasts

 

Many assets do not meet their pre-launch predictions, either exceeding or falling short of their forecast sales. In this article, In Vivo highlights several historic examples and the factors that influenced their unexpected performance.

Podcast: “They Are Able To Keep Their Body”: Medipost On Its Stem Cell Therapy Vision

 

In Vivo spoke with Edward Ahn, CEO of Medipost, a Korean company that has developed stem cell therapies from cord blood, on how they are working across regulatory markets to provide a novel treatment for degenerative diseases.

Can Italy Shake Off Its Reputation And Become A Premier Hub For Biotech?

 
• By 

Leading industry experts have spoken to In Vivo about how investment, a change in mindset and a fresh approach to policy may allow Italy to kick-start its biotech ecosystem.