Getting Late Stage Products Early

Thanks to its speedy deal with Zentaris (a subsidiary of Degussa), two-year old discovery-based start up Ardana Bioscience has leaped into the clinic with a phase II product. Now it's planning more late-stage deals, hoping that investors who typically ignore early-stage companies will finance a commercially focused organization with a track record of in-licensing the right drugs.

When Ardana PLC was set up in July 2000 to commercialize work generated by the Medical Research Council (MRC)'s Human Reproductive Sciences Unit (HRSU) in Edinburgh (see "Ardana Bioscience Ltd.," START UP, December 2000 [A#2000900217]), it was always CEO and serial entrepreneur Simon G. Best's intention to turn the company as quickly as possible into a specialty pharmaceutical firm with marketed products. But the current environment, in which investors have little time—or money—for risky biotech plays that are still years from seeing any revenues, likely accelerated the process.

Paying €6.25 million ($6.1 million) upfront, with a further €21.75 million in potential milestones, to Zentaris AG, the biopharmaceutical division of Degussa AG , didn't quite bring Ardana a...

More from Global Vision

UK Bets On Regulatory Innovation As Competitive Advantage In Synthetic Biology

 
• By 

The UK government has prioritized synthetic biology and created a "concierge service" for biotechs just as the US cuts science funding.

Chinese Firms Build Obesity Clinical Pipeline But Face Wider Hurdles

 
• By 

Despite the ability to initiate clinical trials quickly and having strong manufacturing capacity, Chinese companies are facing multiple challenges in the obesity space.

Unpacking The Impact Of Trump’s Tariffs On Drug Pricing And Production

 
• By 

Big pharma plans to invest billions of dollars in US manufacturing to avoid tariffs proposed by the Trump Administration. However, the implementation of these plans may be delayed due to regulatory complexities and rising costs from tariffs, potentially impacting drug prices for consumers.

Barcelona’s S2 Xpeed Accelerates Hardware-Based Medtech Start-Ups From Prototype To Market

 
• By 

S2 Xpeed is driving the rapid growth of medtech and hardware start-ups in Europe. Operating under a "sweat equity" model, the program helps early-stage companies move from prototype to manufacturing readiness in exchange for equity.

More from In Vivo

The 360 Degrees Of European Biotech Financing In 2025

 
• By 

Almost halfway through 2025, and financing for European biotech could be described as challenging. Market volatility, geopolitical instability and trade barriers all loom large in biotech CEO minds when pitching for funding. In Vivo talked to biotechs and investors to gain a realistic view of the current market for company funding so far this year.

Rising Leaders 2025: Pedro Valencia’s ADC Vision At AbbVie

 
• By 

From chemical engineering to cancer innovation, AbbVie's rising oncology leader is advancing next-generation ADCs to tackle difficult-to-treat tumors with a patient-centered approach.

Leaders At The Frontier: Conversations From SynBioBeta 2025

 
• By 

Mini-profiles of five synthetic biology companies and their leaders from SynBioBeta 2025 reveal how AI integration, data-driven platforms and interdisciplinary teams are revolutionizing drug discovery and manufacturing.