Ark Therapeutics: Spreading, or Hiding Risk?

Since its IPO in March 2004, Ark Therapeutics has been watched closely, as the first European biotech to float in nearly three years. Critics point to a lack of strategic focus, claiming the broad collection of products in the firm's portfolio, including a device, drugs and even a diagnostic, will be difficult to exploit in a small company with limited resources. Yet diversity apparently proved an attractive feature-particularly to generalist investors who see the company as a spread risk bet on biotech. It has also allowed Ark to hide the far higher risk associated with individual follow-up programs, where most of the firm's value lies, behind a sure-bet marketed product.

When Ark Therapeutics Group PLC announced its intention to IPO in early 2004, numerous commentators questioned the company's chances of success. An earlier attempt to IPO in 2002 had failed and the firm lacked strategic focus, the skeptics contended. In the event, the size and scope of Ark's March 2004 IPO suggested they were wrong. Ark raised £55 million ($102 million) in one of the largest biotech flotations globally since the IPO window opened in the US in the second half of 2003 (second only to Eyetech Inc. 's $146 million Nasdaq listing concluded in January 2004 [See Deal]). The offer was three times oversubscribed despite being priced in the middle of the offer range [See Deal].

Since then however Ark's stock has fallen over 14% to 113.5p. (See Exhibit 1.) Yet so have the prices of...

More from Global Vision

More from In Vivo

Podcast: ADDF’s Karen Harris On Investing In Alzheimer’s Like A VC

 
• By 

A discussion with Karen Harris, CFO of the Alzheimer's Drug Discovery Foundation, about the foundation's investment strategy, biotech and investor sentiment at the recent BIO conference and what innovations give her hope for Alzheimer's patients.

Turning Defense Into Attack: Snapshots Of A Changing Medtech Market And How To Respond

 
• By 

Against a backdrop of shifting trade policies, the end of multilateral market approaches and renewed focus on supply chain resilience, medtechs are doubling down on innovation in products and processes – using AI – and keeping unmet needs and outcomes in the center of the target.

AI Agents Set To Reshape Biopharma’s Workforce And Operations

 
• By 

While biopharma companies experiment with genAI, agentic AI is rapidly shifting the work paradigm towards one of autonomous digital workers that can handle entire process flows.