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What Does It Take To Launch And Lead An Oncology Biotech Today?

An Interview With Theolytics CEO Charlotte Casebourne

 
• By Lucie Ellis-Taitt

Oncolytic virus company Theolytics has emerged ready to raise a series A round and get its preclinical assets into human trials by 2021. CEO Charlotte Casebourne talks to In Vivo about the challenge of standing out from the crowd in oncology, how viruses have evolved as a treatment approach in cancer, and how oncolytic viruses might be able to answer the cancer drug pricing conundrum.

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• Source: Shutterstock

To date the oncolytic virus field has focussed on the slow, careful design of therapeutic viruses – an approach dependent on the human mind creating the best possible virus from thousands of base pairs. However, Theolytics is leveraging a convergence of emerging technologies within the viral therapy field – long-read sequencing, sophisticated bioinformatics and advanced genetic engineering – to accelerate discovery and development.

The company launched with £2.5m in seed investment from Oxford Sciences Innovation (OSI), a £600m fund focused on commercializing ideas...

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