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Restoring Balance In The Gut To Prevent Drug-Resistant Infection

 
• By Joseph Haas

Silvia Caballero, one of In Vivo’s 2020 Rising Leaders, is heading up Vedanta’s efforts to prevent potentially lethal infections stemming from colonization of the gut microbiome with a novel bacterial cocktail that is nearing clinical development.

Bacterias 3D rendering

A number of biotechs and academic researchers are investigating ways to fight drug-resistant pathogens, but Vedanta Biosciences Inc. is working to advance a novel approach toward clinical development – bringing balance back to a patient’s microbiome and using “good” gut bacteria to neutralize bad bacteria and stave off infections in at-risk patients.

Heading up this effort at the Cambridge, MA-headquartered firm is Silvia Caballero, leader of a five-person team focused on multi-drug-resistant...

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