1. In Vivo

The 14 Billion Dose COVID-19 Manufacturing Challenge

mRNA Vaccines Leading The Way

 
• By Andrew McConaghie

Manufacturing COVID-19 vaccines at unprecedented speed and scale is 2021’s biggest challenge – and mRNA platforms are emerging as the leaders, living up to their promise as the ideal technology for pandemic preparedness.

Vaccinate the world
10 major COVID-19 vaccines have now been authorized worldwide, but the production challenge remains formidable.

The development of the first COVID-19 vaccines in 2020 was undoubtedly one of the greatest ever achievements of the biopharma sector and its partners, with the first vaccines discovered, tested in Phase III trials and granted emergency use authorization in less than 12 months.

This has transformed expectations about how fast a vaccine can be developed, condensing the work of 5-10 years into just one.

What makes these achievements even more remarkable is that it was the first time vaccines had been brought to patients using these platforms – messenger RNA (mRNA) in the case...

More from COVID-19

More from In Vivo

The 360 Degrees Of European Biotech Financing In 2025

 
• By Jo Shorthouse

Almost halfway through 2025, and financing for European biotech could be described as challenging. Market volatility, geopolitical instability and trade barriers all loom large in biotech CEO minds when pitching for funding. In Vivo talked to biotechs and investors to gain a realistic view of the current market for company funding so far this year.

Rising Leaders 2025: Pedro Valencia’s ADC Vision At AbbVie

 
• By Jo Shorthouse

From chemical engineering to cancer innovation, AbbVie's rising oncology leader is advancing next-generation ADCs to tackle difficult-to-treat tumors with a patient-centered approach.

Leaders At The Frontier: Conversations From SynBioBeta 2025

 
• By David Wild

Mini-profiles of five synthetic biology companies and their leaders from SynBioBeta 2025 reveal how AI integration, data-driven platforms and interdisciplinary teams are revolutionizing drug discovery and manufacturing.