In 2017, the US Food and Drug Administration approved Novartis AG’s Kymriah for the treatment of patients with acute lymphocytic leukaemia (ALL). The decision marked a sea change – Kymriah became the first of several chimeric antigen receptor (CAR) T-cell therapies to enter the cancer market.
CAR-T cell treatment involves taking T-cells from patients’ blood, enhancing them in the lab by adding a gene for a...