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Marinus On Track To Be Leader In Rare Epilepsy Market, Says CEO

Strategic Collaborations, Creative Financing And Late-Stage Data Readouts

 
• By Lucie Ellis-Taitt

CEO Scott Braunstein, who took leadership of Marinus in 2019 following clinical trial setbacks, believes the company is on a route to success with its ganaxolone program, targeting chronic use and hospital markets. 

Brain scan
• Source: Shutterstock

Marinus Pharmaceuticals, Inc.’s Ztalmy (ganaxolone) won European Commission approval in July 2023 as an oral treatment for seizures associated with a rare, genetic pediatric-onset epilepsy disorder. The drug was previously approved by the US FDA in March 2022, which marked an important moment for the company, as the drug had previously failed in clinical trials for Fragile X syndrome and post-partum depression.

Ztalmy, a positive allosteric modulator of the GABAA receptor for the treatment of seizures associated with cyclin-dependent kinase-like 5 (CDKL5)...

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