As Casgevy, Lyfgenia Launches Proceed, CRISPR And bluebird bio CEOs Reassure

The CEOs of bluebird bio and CRISPR Therapeutics hope to inspire investor confidence that their gene-based therapies for sickle cell disease and beta thalassemia will be widely reimbursed in the US and EU.  

Waiting For Market Uptake Of Competing Gene-Based Therapies • Source: Shutterstock

As investors and industry observers track the launch of Casgevy (exagamglogene autotemcel) and Lyfgenia (lovotibeglogene autotemcel), gene-based therapies approved in December 2023 for certain sickle cell disease and beta thalassemia patients, the CEOs of CRISPR Therapeutics AG and bluebird bio are exuding confidence that all will go well commercially.

“I don’t see fundamental roadblocks or fundamental issues as we look at these launches,” Samarth Kulkarni, CEO of CRISPR Therapeutics,...

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