UK- and Australian-based Grey Wolf Therapeutics, Ltd.’s lead clinical development candidate, GRWD5769, a selective oral ERAP1 inhibitor, has shown the potential to elicit a “powerful and differentiated immune response against tumors,” the company highlighted in a recent data readout.
A second ERAP1 inhibitor, GRWD0715, is advancing through preclinical development as a potential treatment for autoimmune disease.